Pathophysiology of Preeclamsia

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Published Jul 30, 2022
https://doi.org/10.25077/jom.7.1.94-102.2022
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Vol. 7 No. 1 (2022): Published on June 2022

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Hudila Rifa Karmia
Department Of Obstetrics and Gynecology, Medical Of Faculty, Andalas University, Padang, West Sumatera, Indonesia
Joserizal Serudji
Department Of Obstetrics and Gynecology, Andalas University Hospital, Padang, West Sumatera, Indonesia

Abstract

The uncertainty of the etiology and underlying mechanisms of the pathophysiology of this disease makes causal structuring and primary prevention of preeclampsia impossible, making it difficult to control morbidity and mortality, both maternal and perinatal. From the many theories on preeclampsia, the disease can be classified into Placental preeclampsia, maternal preeclampsia, and Vascular Disorders of Pregnancy (VDP). Increased inflammatory response to placental factors, excessive inflammatory response to placental factors, and primary vascular disorders are the basis of distinction and also the basis of pathophysiology among the three forms of preeclampsia.

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