Email this article Relationship Between Ferritin and Folic Acid Levels In Pregnant Women With Newborn Weight and Head Circumference
DOI: http://dx.doi.org/10.25077/jom.3.2.113-126.2018
Author(s)
Usna Maria Harahap
(Andalas University)
Fadil oenzil (Andalas University)
Desmawati Desmawati (Andalas University)
Abstract
Iron deficiency and folic acid anemia cause decrease in ferritin and folic acid levels that can interfere with the intake of oxygen and nutrients to the fetus resulting in LBW and reduced brain growth during pregnancy. The aim of the study was to determine the relationship between ferritin and folic acid levels in pregnant women with newborn weight and head circumference.
This study was a cross sectional study conducted on 55 pregnant women at 37-42 weeks who were taken by consecutive sampling technique. The study was carried out in the Working Area of the Puskesmas and the Regional Health Laboratory of the Merangin Regency, and the health laboratory of West Sumatra Province from May 25 to July 13, 2018. Test the normality with the Kolmogorov-smirnov test and the correlation test using Pearson and Spearman.
The results showed ferritin mean 23,643±16,682 ng/ml, folic acid 14,093±4,578 ng/ml, newborn weight 3047,27±399,005 gram and head circumference 33,02±1,163 cm. Statistical test results showed no correlation between ferritin levels with body weight (r=0.063, p=0.648) and head circumference (r=0.018, p=0.895) and folic acid levels with body weight (r=-0.036, p=0.795) and head circumference (r=-0.098, p=0.477).
The conclusions of the study were that ferritin and folic acid levels of pregnant women had no significant correlation with newborn weight and head circumference. By improving nutrition, socioeconomic, qualitative antenatal care, initial referral of risky cases and supplementation of iron and folic acid can reduce the incidence of anemia.Keywords
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Ahmed, A. Akhter, M. Sharmin, S. Ara, S. Hoque, MM. (2011). Relationship of maternal folic acid and vitamin B12 with birth weight and bodyproportion of newborn. J. Dhaka National Med. Coll. Hos 2011; 18 (01): 7-11
Ali, SM. Murad, AM. Murad, AM. (2015). Effect of maternal hemoglobin on anthropometric measurements of full term newly born babies. Al-nahrain college of medicine. ISSN 1681-6579
Almatsier, S. (2004). Prinsip dasar ilmu gizi. Jakarta: Gramedia pustaka utama
Bickley, LS. (2015). Buku ajar pemeriksaan fisik & riwayat kesehatan edisi 11. Jakarta: EGC
Bothamley, J andBoyle, M. (2010). Patofisiologi dalam kebidanan. Jakarta: EGC
Chowdhury, S. Rahman, M. Moniruddin, ABM. (2014). Anemia in pregnancy. Medicine Today, Vol. 26, No. 01
Darwanty, J andAntini, A. (2011). Kontribusi asam folat dan kadar hemoglobin pada ibu hamil terhadap pertumbuhan otak janin. Poltekkes Kemenkes bandung. Bandung. Diakses 16 Februari 2017. http://ejournal.litbang.depkes.go.id/index.php/kespro/article/view/3922
De Graaff, JS. Roza, SJ. Walstra, AW. Marroun, HE. Steegers, EA. Jaddoe, VWV, et al. (2015). Associations of maternal folic acid supplementation and folate concentrations during pregnancy with foetal and child head growth: the generation R study. Eur J Nutr doi: 10.1007/s00394-015-1058-z
De Sa, SA. Willner, E. Pareira, TAD. De Sa, S. Boaventura, GT. De Azeredo, VB. (2015). Anemia in pregnancy: impact on weight and in the development of anemia in newborn. Nutr Hosp;32(5): 2071-2079. ISSN 0212-1611
Dinas Kesehatan Kabupaten Merangin. (2015). Laporan capaian indikator program KIA tahun 2015 kabupaten merangin. Bangko: Dinas Kesehatan Kabupaten Merangin
Dinas Kesehatan Kabupaten Merangin. (2016). Laporan pencapaian indikator KIA dan gizi kabupaten merangin tahun 2016. Bangko: Dinas Kesehatan Kabupaten Merangin
Departemen gizi dan kesehatan masyarakat. (2011). Gizi dan kesehatan masyarakat. Jakarta: PT. Rajagrafindo Persada.
Dinas Kesehatan Provinsi Jambi. (2015). Profil kesehatan provinsi jambi 2014. Jambi: Dinas Kesehatan Provinsi Jambi.
Dinas Kesehatan Provinsi Jambi. (2016). Profil kesehatan provinsi jambi 2015. Jambi: Dinas Kesehatan Provinsi Jambi.
Dwijayanthi, L. Nugroho, AW. Santoso, N(eds). (2011). Ilmu Gizi menjadi sangat mudah Edisi 2. Jakarta: EGC
Eneroth, H. (2011). Infant anemia and micronutrient status, studies of early determinants in Rural Bangladesh. Universitas Upsaliensis Uppsala. ISSN 1651-6206. ISBN 978-91-554-7992-3
Fatima, E. Fatima, E. Suher, A. Eatedal, M. Reham, A. Hiba, B, et al. (2017). The correlation between maternal hemoglobin level and neonatal birth weight. Int. J of multidisciplinary and current research, vol.5
Fikawati, S. Syafiq, A. Karima, K. (2015). Gizi ibu dan bayi. Jakarta: PT. Rajagrafindo persada.
Fraser, DM andCooper, MA(eds). (2011). Myles buku ajar bidan (Edisi 14). Jakarta: EGC
Gaur, S. Kataria, SK. Agarwal, R. (2015). A study effects of maternal anaemia on anthropometrics measurements of newborns. The pharma innovation journal 2015; 4(8): 69-71. ISSN: 2277-7695
Gibney, MJ.Margaretts, BM. Kearney, JM. Arab, L(eds). (2008). Gizi kesehatan masyarakat (Public health nutrition). Jakarta: EGC
Grober, U. (2012). Mikro-nutrien: penyelarasan metabolic, pencegahan dan terapi (micronutrients: metabolic tuning-prevention-therapy). Jakarta: EGC
Hadipour, R. Norimah, AK. Poh, BK. Firoozehchian, F. Hadipour, R. Akaberi, A. (2013). Haemoglobin and serum feritin levels in newborn babies born to anaemic Iranian women: a cross sectional study in an Iranian hospital. Pakistan journal of nutrition 9 (6): 562-566, 2010. ISSN: 1680-5194
Hanafiah, TM. (2006). Perawatan antenatal dan peranan asam folat dalam upaya meningkatkan kesejahteraan ibu hamil dan janin. Pidato Pengukuhan Jabatan Guru Besar Tetap dalam Bidang Ilmu Kebidanan dan Penyakit Kandungan pada Fakultas Kedokteran.Universitas Sumatera Utara. Medan.
Jiang, HL. Cao, LQ. Chen HY. (2016). Blood folic acid, vitamin B12 and homocysteine levels in pregnant women with fetal growth restriction. Genetics and molecular research 15 (4): gmr15048890.
Joseph andNugroho, S. (2010). Catatan kuliah ginekologi danobstetric (Obsgyn) untuk keperawatan dan kebidanan. Yogyakarta: Nuha Medika
Kalem, P. Benli, AR. Koroglu, M. Benli, NC. Koyuncu, M. Cesur, O, et al. (2016). The effect of ferritin, vitamin B12 and folic acid on pregnancy outcomes. Int J Clin Exp Med 2016; 9(11): 22413-22147. ISSN: 1940-5901/IJCEM0031551
Kaur, M. Chauhan, A. Manzar, MD. Rajput, MM.(2015). Maternal anaemia and neonatal outcome: a prospective study on urban pregnant women. Journal of clinical and diagnostic research. DOI: 10.7860/JCDR/2015/14924.6985
Kozuma, S. (2009). Approaches to anemia in pregnancy. Research and reviews JMAJ 52(4): 214-218.
Nagmoti, SA. Walvekar, PR. Mallapur, MD. (2015). Association between body mass index of mother and anthropometry of newborn. Int J Med Res Health Sci 4(4): 796-798. DOI: 10.5958/2319-5886.2015.00157.5
Passerini, L. Casey, GJ. Biggs, BA. Cong, DT. Phu, LB. Phuc, TQ, et al. (2012). Increased birth weight associated with regular pre-pregnancy deworming and weekly iron-folic acid supplementation for Vietnamese women.Diakses 16 Februari 2017. http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.000160
Proverawati, A. (2011). Anemia dan anemia kehamilan. Yogyakarta: Nuha Medika
Rajab, W. (2009). Buku ajar epidemiologi untuk mahasiswa kebidanan. Jakarta: EGC
Rofingatul, M. Tejayanti, T.Senewe, FP.(2010). Hubungan kematangan reproduksi dan usia saat melahirkan dengan kejadian bayi berat lahir rendah (BBLR) di Indonesia tahun 2010. Jurnal kesehatan reproduksi (ISSN 2087-703X) Vol.7, No. 2 (2016), pp. 109-118
Satyam, P andKhushbu, Y. (2015). Maternal anemia in pregnancy: An overview. Review article, Vol. 4, Issue: 3: 164-179
Septiyani, W. Lipoeto, NI. Serudji, J. (2016). Hubungan asupan asam folat, zink, vitamin A ibu hamil terhadap berat badan lahir di kabupaten padang pariaman. Jurnal kesehatan andalas 2016; 5(1)
Shaikh, S. Iftequar, S. Zaheer, Z. Khan, MM. Khan, S. (2015). An overview of anemia in pregnancy. JIPBS, Vo. 2 (2), 144-151
Sharma, JB andShankar, M. (2010). Anemia in pregnancy. JIMSA October-December 2010, Vol. 23, No. 4Sherwood, L. (2011). Fisiologi manusia: dari sel ke sistem. Jakarta: EGC
Siddappa, AM. Rao, R.Long, JD. Widness, JA. Georgieff, MK. (2010). The assessment of newborn iron stores at birth: a review of the literature and standards for feritin concentrations. DOI: 10.1159/000100805
Soetjiningsih andRanuh, IGNG. (2013). Tumbuh kembang anak (Edisi 2). Jakarta: EGC
Sudikno andSandjaja. (2011). Prevalensi dan faktor risiko anemia pada wanita usia subur di rumah tangga miskin di kabupaten tasikmalaya dan ciamis, provinsi jawa barat. Jurnal kesehatan reproduksi (ISSN 2087-703X) Vol. 7, No. 2 (2016), pp: 71-82
Survei Demografi dan Kesehatan Indonesia(SDKI). (2012). Diakses 17 Januari 2018. http://chnrl.org/pelatihan-demografi/SDKI-2012.pdf
Syah, MNH. Thaha, AR. Citrakesumasari. (2012). Status zat gizi mikro (besi, asam folat dan seng) dan kerusakan DNA pada anemia ibu hamil di kecamatan bontonompo dan botonompo selatan kabupaten gowa tahun 2012.Diakses 16 Maret 2017.
Tangkilisan, HA andRumbajan, D. (2002). Defisiensi asam folat.Sari pediatric, Vol. 4, No. 1, Juni 2002: 21-25
Telatar, B. Comert, S. Vitrinel, A. Erginoz, E. Akin, Y. (2009). The effect of maternal anemia on anthropometric measurements ofnewborns. Saudi Med J: 409-12
Waryana. 2010. Gizi reproduksi. Yogyakarta: Pustaka Rihama.
Wibowo, T. (2010). Buku saku pelayanan kesehatan neonatal esensial; Pedoman teknis pelayanan kesehatan dasar. Jakarta: Kementerian Kesehatan RI
World Health Organization (WHO). (2012). Guideline: Daily iron and folic acid supplementation in pregnant women.
Wylie, L andBryce, H. (2010). Manajemen kebidanan gangguan medis kehamilan dan persalinan. Jakarta: EGC
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Copyright (c) 2018 Usna Maria Harahap, Fadil oenzil, Desmawati Desmawati
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Undergraduate Program of Midwifery
Faculty of Medicine - Universitas Andalas - Indonesia
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.