Association of Pesticides Exposure with Breast Cancer in West Sumatera Province, Indonesia



DOI: https://doi.org/10.25077/jom.4.2.8-14.2019


Author(s)

Yuniar Lestari (Department of Public Health and Community Medicine, Faculty of Medicine, Universitas Andalas, Padang)
Rima Semiarty (Department of Public Health and Community Medicine, Faculty of Medicine, Universitas Andalas, Padang)
Wirsma Arif Harahap (Department of Surgical Oncology, Faculty of Medicine, Universitas Andalas, Padang)

Abstract


Breast cancer cause multifactorial, one of the risk factors is exposure of pesticides. The aim of this study was to determine association of pesticides exposure with breast cancer in West Sumatera Province, Indonesia. In this cross sectional study, the data were collected from Dr. M Djamil General Hospital Padang. Sampling technique with convenience sampling. We selected 234 patients with breast cancer diagnosed. The variables of this study included independent variable is exposure pesticides and dependent variable is breast cancer. Pesticides exposure were collected from the questionnaire of pesticides exposure that have been validated. The association was analyzed by using chi-square test and cut off point analyzed using receiver operating characteristics (ROC). A two-tailed P-value of <0.05 was considered statistically significant. Data  were  analyzed  using  the SPSS version 22.0. The results of study found that more than half of respondents (53.8%) were exposed of pesticides while less than half of respondents (46.2%) were not exposed. This study confirmed no association of pesticides exposure with breast cancer in West Sumatera Province, Indonesia

Full Text:

PDF

References


Anders CK, Johnson R, Litton J, Phillips M, 2009. Blayer A. Breast cancer before age 40 years. Semin Oncol. 36(3):237-49.

Anders CK, Johnson R, Litton J, Phillips M. Blayer A. Breast cancer before age 40 years. Semin Oncol. 2009; 36(3):237-49.

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424.

Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and survival in the carolina breast cancer study. JAMA. 2006;295:2492–502.

Harahap WA, Ramadhan Khambri D, et al. Outcomes of trastuzumab therapy for 6 and 12 months in Indonesian national health insurance system clients with operable HER2-positive breast cancer. Asian Pac J Cancer Prev. 2017;18:1151–7

Jones R, Leonard RCF. Treating elderly patients with breast cancer. Breast cancer online. 2005; 8(4):118-22.

Maas P, Barrdahl M, Joshi AD, Auer PL, Gaudet MM, Milne RL et al. Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States. JAMA Oncol. 2016; 1;2(10): 1295-302.

Nindrea RD, Aryandono T, Lazuardi L. Breast cancer risk from modifiable and non-modifiable risk factors among women in Southeast Asia:a meta-analysis. Asian Pac J Cancer Prev. 2017;18:3201–6.

Nindrea RD, Harahap WA, Aryandono T, Lazuardi L. Association of BRCA1 Promoter methylation with breast cancer in Asia:a meta- analysis. Asian Pac J Cancer Prev. 2018;19:885–9.

Nindrea RD, Aryandono T, Lazuardi L, Dwiprahasto I. Association of Overweight and Obesity with Breast Cancer During Premenopausal Period in Asia: A Meta-Analysis. Int J Prev Med. 2019; 10: 192.

Tyrer J, Duffy SW, Cuzick J. A breast cancer prediction model incorporating familial and personal risk factors. Stat Med. 2004; 23; 1111-1130.


Article Metrics

This article has been read : 544 times
PDF file viewed/downloaded : 429 times

Copyright & License


Copyright (c) 2020 Yuniar Lestari

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Published by:
Undergraduate Program of Midwifery
Faculty of Medicine - Universitas Andalas - Indonesia
Faculty of Medicine, Universitas Andalas

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.