Antioxidant supplementation during in vitro maturation



DOI: https://doi.org/10.25077/jom.4.2.1-7.2019


Author(s)

Amalia Ratna Kusumaningrum (Master of Reproductive Health, Faculty of Medicine Airlangga University, Prof Moestopo Street 47, Surabaya 60132, Indonesia)

Abstract


During in vitro maturation (IVM), oocytes are exposed to different situations from in vivo which may cause oxidative stress. Supplementation of antioxidants to the culture media is effective in as antioxidant defences against reactive oxygen species (ROS). Antioxidant is safe, it has some side effects. This is reviewed in this paper. Studies reported, supplementation antioxidant with different dose showed different effects. Double-edged effects of exogenous antioxidants on cellular responses during in vitro maturation depending potentially on their concentrations. Physiologic doses leading to beneficial effects whereas high doses may result in harmful effects.

Keywords


Antioxidant, in vitro maturation, infertility, oocyte, reactive oxygen species (ROS)

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References


Abdel-Daim, M.M., K. Abo-EL-Sooud., L. Aleya., S.G. Bungǎu., A. Najda., R. Saluja. 2018. Alleviation of Drugs and Chemicals Toxicity: Biomedical Value of Antioxidants. Oxidative Medicine and Cellular Longevity. Volume 2018:2.

Barros, V.R.P., A.P.O. Monte., J.M.S. Santos., T.L.B.G. Lins., A.Y.P. Cavalcante., B.B. Gouveia., M.C. Müller., J.L.O. Junior., R.S. Barberino., N.J. Donfack., V.R. Araújo., M.H.T. Matosa. 2019. Effects of melatonin on the in vitro growth of early antral follicles and maturation of ovine oocytes. Domestic Animal Endocrinology (16 August 2019): 106386.

Bennett, L.R., B. Wiweko., A. Hinting., I.B.P. Adyana., M. Pangestu. 2012. Indonesian infertility patients’ health seeking behaviour and patterns of access to biomedical infertility care: an interviewer administered survey conducted in three clinics. Reprod Health. 2012; 9: 24.

Bouayed, J. and T. Bohn. 2010. Exogenous Antioxidants—Double-Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses Versus Deleterious Effects at High Doses. Oxid Med Cell Longev. 2010 Jul-Aug; 3(4): 228–237.

Chowdury, M.M.R., B.H. Choi., I. Khan., K.L. Lee., A. Mesalam., S.H. Song., L. Xu., M.D. Joo., F. Afrin., I. Kong. 2017. Supplementation of lycopene in maturation media improves bovine embryo quality in vitro. Theriogenology. Vol. 103(2017):173-184.

Dornelles, L.M.N., F. MacCallum., R.C.S. Lopes., C.A. Piccinini., E.P. Passos. 2016. The experience of pregnancy resulting from Assisted Reproductive Technology (ART) treatharment: A qualitative Brazilian study. Women and Birth. 2016; Vol. 29(2):123-127.

ElHussein, O.G., M.A. Ahmed., S.O. Suliman., I.I. Yahya., I. Adam. 2019. Epidemiology of infertility and characteristics of infertile couples requesting assisted reproduction in a low-resource setting in Africa, Sudan. Fertil Res Pract. 2019; 5: 7.

El-Hayek, S., H.J. Clarke. 2015. Follicle-Stimulating Hormone Increases Gap Junctional Communication Between Somatic and Germ-Line Follicular Compartments During Murine Oogenesis. Biology of Reproduction, Vol. 93(2), 1 August 2015;47, 1-10.

Emanuelli, I.P., Costa C.B., Rafagnin M.L.S., Seneda M.M., Meirelles F.V. 2019. Cumulus-oocyte interactions and programmed cell death in bovine embryos produced in vitro. Theriogenology. 2019 Mar 1;126:81-87.

Gaviria, S.M. A.L. Herrera., G.R. Betancur., R. Urrego., J.J.E. Zuluaga. 2019. Supplementation with resveratrol during culture improves the quality of in vitro produced bovine embryos. Livestock Science 221 (2019) 139 -143.

Harzif, A.K., V.P.A. Santawi., S. Wijaya. 2019. Discrepancy in perception of infertility and attitude towards treatment options: Indonesian urban and rural area. Reprod Health. 2019; 16: 126.

Hatirnaz, S., B. Ata., E.S. Hatirnaz., M.H. Dahan., S. Tannus., J.

Tan., S.L. Tan. 2018. Oocyte in vitro maturation: A sytematic review. Turk J Obstet Gynecol. 2018 Jun; 15(2): 112–125.

Huang, Dejian. 2018. Dietary Antioxidants and Health Promotion. Antioxidants (Basel). 2018 Jan; 7(1): 9.

Javvaji, P.K., A. Dhali., J.R. Francis., A.P. Kolte., A. Mech., L. Sathis., S.C. Roy. 2019. Interleukin-7 improves in vitro maturation of ovine cumulus-oocyte complexes in a dose dependent manner. Cytokine 113 (2019) 296-304.

Junyu Nie., K. Yan., L. Sui., H. Zhang., H. Zhang., X. Yang., S. Lu., K. Lu., X. Liang. 2020. Mogroside V improves porcine oocyte in vitro maturation and subsequent embryonic development. Theriogenology. Volume 141 (2020): 35-40.

Khajeh, M., R. Rahbarghazi., M. Nouri., M. Darabi. 2017. Potential role of polyunsaturated fatty acids, with particular regard to the signaling pathways of arachidonic acid and its derivatives in the process of maturation of the oocytes: Contemporary review. Biomedicine & Pharmacotherapy. Volume 94 (2017): 458-467.

Khan, Imran., M.M.R. Chowdhury., Seok-Hwan Song., A. Mesalam., Shimin Zhang., A.A.K. Khalil., Eun-Hee Jung., Ju-Boong Kim., L. Jafri., B. Mirza., and Il-Keun Kong. 2018. Lupeol Supplementation Improve the Developmental Competence of Bovine Embryos In Vitro. Theriogenology 107 (2018) 203e210.

Khazaei, M., F. Aghaz. 2017. Reactive Oxygen Species Generation and Use of Antioxidants during In Vitro Maturation of Oocytes. Int J Fertil Steril. 2017 Jul-Sep; 11(2): 63–70.

Kyung S.L., S.J. Chae., C.W. Choo., Y.H. Ku., H.J. Lee., C.Y. Hur., J.H. Lim., W.D. Lee. 2013. In vitro maturation: Clinical applications. Clin Exp Reprod Med. 2013 Dec; 40(4): 143–147.

Lobo, V., A. Patil., A. Phatak., N. Chandra. 2010. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Rev. 2010 Jul-Dec; 4(8): 118–126.

Rocha-Frigoni, N.A.S., B.C.S. Leão., P.C. Dall’Acqua., and G.Z. Mingoti. 2016. Improving the Cytoplasmic Maturation of Bovine Oocytes Matured In Vitro with Intracellular and/or Extracellular Antioxidants Is Not Associated with Increased Rates of Embryo Development. Theriogenology. Vol. 86(8):1897-1905.

Salehi, B., M. Matorell., J.L. Arbiser., A. Sureda., N. Martins., P.K. Maurya., M. Sharifi-Rad., P. Kumar., J. Sharifi-Rad. 2018. Antioxidants: Positive or Negative Actors?. Biomolecules. 2018 Dec; 8(4): 124.

Salimi, M., M. Salehi., R.M. Farahani., M. Dehghani., M. Abadi., M.G. Novin., M. Nourozian., A. Hosseni. 2014. The Effect of Melatonin on Maturation, Glutathione Level and Expression of H MGB1 Gene in Brilliant Cresyl Blue (BCB) Stained Immature Oocyte. Cell J. 2014 Winter; 15(4): 294–301.

Santos, E.C.D., R. Varchetta., C.B. de Lima., J. Ispada., H.S. Martinho., P.K. Fontes., M.F.G. Nogueira., B. Gasparrini., and M.P. Milazzotto. 2019. The effects of crocetin supplementation on the blastocyst outcome, transcriptomic and metabolic profile of in vitro produced bovine embryos. Theriogenology 123 (2019):30-36.

Silva, S.G., A.D. Bertoli., M.F. da Silveria., M.R. Domingues., K.R. Evenson., I.S. dos Santos. 2019. Assisted reproductive technology: prevalence and associated factors in Southern Brazil. Rev Saude Publica. 2019; 53: 13.

Sovernigo, T.C., P.R. Adona., P.S. Monzani., S. Guemra., F.D.A Barros., F.G. Lopes., and C.L.V. Leal. 2017. Effects of Supplementation of Medium with Different Antioxidants During In Vitro Maturation of Bovine Oocytes on Subsequent Embryo Production. Reprod Dom Anim. 2017; 52:561 – 569.

Torres-Osorio, V., R. Urrego., J.J. Echeverri-Zuluaga., A. López-Herrera. 2019. Oxidative stress and antioxidant use during in vitro mammal embryo production. Review. Rev Mex Cienc Pecu 2019;10(2):433-459.

Walls, M.L. and R.J. Hart. 2018. In Vitro Maturation. Best Practice & Research Clinical Obstetrics & Gynaecology. Volume 53:60-72.

Xiao H., L. Cheng., X. Wang., G. Luo., T. Zhao., J. Tian., L. An. 2019. N-acetyl-l-cysteine protects porcine oocytes undergoing meiotic resumption from heat stress. Reproductive Toxicology. Available online 4 November 2019.

Zabihi, A., H.K. Shabankareh., H. Hajarian., and S. Forountanifar. 2018. Resveratrol Addition to In Vitro Maturation and In Vitro Culture Media Enhances Developmental Competence of Sheep Embryos. Domestic Animal Endocrinology. Volume 68:25-31.

Zhiqiang F., M. Yang., M. Regouski., I.A. Polejaeva. 2017. Effects of three different media on in vitro maturation and development, intracellular glutathione and reactive oxygen species levels, and maternal gene expression of abattoir-derived goat oocytes. Small Ruminant Research. Volume 147 (2017):106-114.


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Undergraduate Program of Midwifery
Faculty of Medicine - Universitas Andalas - Indonesia
Faculty of Medicine, Universitas Andalas

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