Email this article Correlation of Calcium Levels With The Strenght of Uterus Contraction on The Active Phase of First Stage Labor
DOI: https://doi.org/10.25077/jom.3.2.76-83.2018
Author(s)
Novia Rita Aninora
(Andalas University)
Joserizal Seridji (Department of Obstetrics and Gynecology, Dr. M. Djamil Padang Hospital)
Meilinda Agus (Andalas University)
Abstract
Contributing factor to uterus contraction mechanism is the imbalance of the extracellular calcium level. When extracellular calcium level is inadequate, response of the myometrium to oxytocin decreased and the calcium influx inter-cell membranes are suppressed, thus inhibit uterine contractions. The aim of this research is to know the correlation between levels of calcium and the strength of uterine contraction in the active phase of first stage labor. This was a cross-sectional analytic correlative study in the Dr. Rasidin Hospital Padang and UPTD Health Laboratory in West Sumatra province, in was conducted from November 1st, 2014 till February 2016. Sampling was takes by using non probability sampling with consecutive sampling. Subjects of this research were the active phase of first stage labor of 62 people. Kolmogorof Smirnov normality test was used to the normality of the data. Pearson correlation test was conducted to examine the correlation between dependent and independent variables. Mean levels of calcium in the the stage I of labor respondents active phase (8.94 ±0,71), while mean strength of uterine contractions in active phase of first stage labor(56.77±11,84), there was positive correlation (r = 0,62) between the levels of calcium in the strength of uterine contractions (p < 0.05). The conclusion of the study there was a significant correlation between the levels of calcium in the strength of uterine contractions.
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Acharya, G., Sitras, V., Paulssen, R. H., & Grønaas, H. (2008). Gene expression profile in labouring and non-labouring human placenta near term, 14(1), 61–65.
doi.org/10.1093/molehr/gam083
Aguilar, H. N., & Mitchell, B. F. (2010). Physiological pathways and molecular mechanisms regulating uterine contractility, 16(6), 725–744. doi.org/10.1093/humupd/dmq016
Albers, L. L. (2007). The Evidence for Physiologic Management of the Active Phase of the First Stage of Labor, 207–215.
Anderson. L (2010). The Myometrial Effects of Progesterone Doctor of Medicine Faculty of Medicine University of Glasgow.
Anwar, A. D., Purwara, B. H., & Tjahyadi, D. (2015). Serum Calcium And Magnesium Levels Ratio In Patients With And Without Hypotonic Uterine Inertia, 3(2), 1–11.
Arisman M. (2009). Gizi Dalam Daur Kehidupan. Jakarta: EGC.
Bobak IM,Lowdermilk D, Jensen M, P. S. (2005). Buku ajar keperawatan maternitas (terjemahan). Jakarta: EGC.
Breuiller-fouché, M., Dubois, O., Sediki, M., Garcia-verdugo, I., Palaniyar, N., Tanfin, Z., ... Mehats, C. (2010). Secreted surfactant protein A from fetal membranes induces stress fibers in cultured human myometrial cells, 1188–1197. doi.org/10.1152/ajpendo.00746.2009.
Cunningham FG, Gant NF, Leveno KJ, Gilstrap LC, Hauth JH, W. K. (2010). OBSTETRICS Williams (23rd ed.). McGraw-Hill, New York.
Dahlan, M. S. (2009). Besar Sampel dan Cara Pengambilan Sampel Dalam Penelitian Kedokteran dan Kesehatan. Jakarta: Salemba Medika.
David, T. . L. (2007). Manual Persalinan. Jakarta: EGC.
Fetalvero, K. M., Zhang, P., Shyu, M., Young, B. T., Hwa, J., Young, R. C., & Martin, K. A. (2008). Prostacyclin primes pregnant human myometrium for an enhanced contractile response in parturition, 118(12).
doi.org/10.1172/JCI33800.3966
Fischer, D. P., Hutchinson, J. A., Farrar, D., Donovan, P. J. O., Woodward, D. F., & Marshall, K. M. (2005). Loss of prostaglandin F 2 a , but not thromboxane , responsiveness in pregnant human myometrium during labour. doi.org/10.1677/JOE-07-0494
Fomin VP, Gibbs SG, Vanam R, Morimiya A, Hurd WW. Effect of magnesium sulfate on contractile force and intracellular calcium concentration in pregnant human myometrium. Am J Obstet Gynecol. 2006;194(5):1384-90.
Gao, L., Cong, B., Zhang, L., & Ni, X. (2009). Expression of the calcium-activated potassium channel in upper and lower segment human myometrium during pregnancy and parturition, 9, 1–9. doi.org/10.1186/1477-7827-7-27Gilbert, R.J. (2010). Calcium , parathyroid hormone , oxytocin and pH profiles in the whelping bitch, doi.org/10.1016/j.theriogenology.2009.12.008
Guyton AC, H. J. (2007). Buku Ajar Fisiologi Kedokteran (11th ed.). Jakarta: EGC.
Heimstad R., MD, Eirik Skogvoll, MD, Lars-A ̊ke Mattsson, MD, Ole Jakob Johansen, MD, Sturla H. Eik-Nes, MD, and Kjell A ̊. Salvesen, M. (2007). Induction of Labor or Serial Antenatal Fetal Monitoring in Postterm Pregnancy, 109(3), 609–617.
Hidayat, A. A. (2009). Metode Penelitian Keperawatan dan Teknik Analisis Data. Jakarta: Salemba Medika.
Hutchings, G., Williams, O., Cretoiu, D., & Ciontea, S. M. (2009). Myometrial interstitial cells and the coordination of myometrial contractility, 13(10), 4268–4282.
https://doi.org/10.1111/j.1582-4934.2009.00894.x
Jenny J.S Sondakh. (n.d.). Asuhan Kebidanan Persalinan & Bayi Baru Lahir. Jakarta: Erlangga.
Jim Mann-A.Stewart. (2014). Ilmu Gizi (4th ed.). Jakarta: EGC.
Kamel, R. M. (2010). The onset of human parturition, 975–982. doi.org/10.1007/s00404-010-1365-9
Kota, S. K., Gayatri, K., Jammula, S., Kota, S. K., Krishna, S. V. S., & Meher, L. K. (2013). Review Article Endocrinology of parturition, 17(1), 50–59. doi.org/10.4103/2230-8210.107841
Lartey, J., & Lo, A. (n.d.). RHO protein regulation of contraction in the human uterus ́. doi.org/10.1530/REP-09-0160
Lestari, S. (2008). Pengaruh pemberian preparat sitrulin-malat terhadap konsentrasi asam laktat ibu bersalin, 32(4).
Linda J. H. (2008). At a Glance Sistem Reproduksi (2nd ed.). Jakarta: Erlangga.
Liu, X., Washington, B., Va, D. C., Tai, K., & National, C. (2007). TRPC1: The link between functionally distinct store-operated calcium channels TRPC1 : The link between functionally distinct store-operated calcium channels,(November 2015).doi.org/10.1016/j.ceca.2007.01.013
Macintyre, D., Chan, E., Macintyre, D. A., Chan, E., & Smith, R. (2007). Myometrial activation -Coordination , connectivity and contractility, (October 2016).doi.org/10.1017/S0965539507002033
Mariati, A., Masrul, D. S., Arasy, Z. A. F., Hanum, M. H., & Arma, M. F. (2007). Studi Kematian Ibu dan Kematian Bayi di Provinsi
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Copyright (c) 2018 Novia Rita Aninora, Joserizal Seridji, Meilinda Agus
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Undergraduate Program of Midwifery
Faculty of Medicine - Universitas Andalas - Indonesia
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.