The Correlation of Retinol Level with Hemoglobin Level in Third Trimester of Pregnancy Woman



DOI: https://doi.org/10.25077/jom.1.1.92-102.2018


Author(s)

Febry Mutiariami Dahlan (Andalas University)
Eryati Darwin (Andalas University)
Hirowati Ali (Andalas University)

Abstract


Bleeding is one of the highest causes of maternal death. Anemia is a major cause of bleeding. Anemia in pregnant women is caused by iron deficiency, meanwhile the achievement of giving Fe tablets is quite high. Factors for anemia due to lack of intake of vitamins A, C, B12 and folate.This study aims to determine the Correlation Retinol Level with Hemoglobin Level and Ferritin Level in Pregnant Women Thiird trimester. This study was conducted using cross sectional approach, from Juli 2017 – February 2018 at Lubuk Buaya Health Center, Andalas Health Center and UNAND Biomedical Laboratory using pregnant women in third trimesteras sample with consecutive sampling technique totalling 44 people. Independent variable is retinol level and dependent variable are hemoglobin and ferritin level. Examination using Hematology Analyzer for hemoglobin and ELISA reader for examination of retinol level and  ferritin level. Data was performed using a computer program to analyze nprmally distributed data using pearson test and spearman test that are abnormally distributed. Mean of retinol level of respondent was 137,612±21,717 ng/ml, hemoglobin 10,916±0,880 gr/dl and ferritin level 26,681±30,829 ng/ml. From result of analysis  pearson test showed that there was a significant correlation between retinol level and hemoglobin level in pregnant women with p=0,001 (p<0,05) dan r=0,473 and there was no significant correlation between retinol level and ferritin level in pregnant women  p=0,158 (p>0,05)  (r=0,216). The conclusion of this study is that there is a correlation of retinol level with hemoglobin level and no correlation of retinol with ferritin level. 

Full Text:

PDF

References


Almatsier, S,Prinsip Dasar Ilmu Gizi, Jakarta: PT Gramedia Pustaka Utama; 2009.

Badan Pusat Statistik, Survei Penduduk Antar Sensus (SUPAS), Jakarta: BPS;2015.

Bakta, IM,Hematologi Klinik Ringkas, Jakarta: EGC; 2015.

Berdanier CD,Nutrient Interaction In Handbook Of Nutrition And Food, 3rd, USA: CRC Press; 2008.

BKKBN, Laporan BKKBN Tahun 2013, Jakarta: BKKBN; 2013.

Briawan, Dodik,Anemia Masalah Gizi Pada Remaja Wanita, Jakarta: EGC; 2014.

Citelli M, Bittencourt LL, da Silva SV, Pierucci AP, and Pedrosa C. "Vitamin A modulates the expression of genes involved in iron bioavailability",Biol Trace Elem Res,Vol. 149, 2012, pp. 64-70.

Citrakesumasari, Anemia Gizi, Masalah dan Pencegahannya, Yogyakarta: Kalika;2012.

Dinkes Kota Padang,Laporan Tahunan Tahun 2015, Padang: Dinas Kesehatan Kota Padang;2016.

Dinkes Prov Sumbar,Profil Kesehatan Provinsi Sumatera Barat Tahun 2014, Padang: Dinkes Provinsi Sumatera Barat;2015.

Hillman, R.S., Ault, K.A., Rinder, and Henry M, Hematology in Clinical Practice, 4th,New York: McGraw-Hill Companies;2011.

Kemenkes RI,Profil Kesehatan Indonesia tahun 2012, Jakarta: Kementrian Kesehatan Republik Indonesia;2013.

Kemenkes RI, Profil Kesehatan Indonesia Tahun 2015, Jakarta: Kementerian Kesehatan Republik Indonesia;2016.

Lu, Zhengda, Dakota O'Dell, Balaji Srinivasan, Elizabeth Rey, Ruisheng Wang, Sasank Vemulapati, Saurabh Mehta, and David Erickson, "Rapid diagnostic testing platform for iron and vitamin A deficiency",Proc Natl Acad Sci USA, Vol. 114, No. 51, 2017, pp. 13513-13518.

Muslimatun, Siti, Marjanka K Schmidt, Werner Schultink, Clive E West, Joseph G.A.J Hautvast, Rainer Gross, and Muhilal, "Weekly Supplementation with Iron and Vitamin A during Pregnancy Increases Hemoglobin Concentration but Decreases Serum Ferritin Concentration in Indonesian Pregnant Women",J Nutr, Vol. 131, 2001. pp. 85-90.

Muthalib, Abdul, Ilmu Kebidanan Sarwono Prawirohardjo. Jakarta: PT Bina Pustaka Sarwono Prawirohardjo; 2010.

Pearce, Evelyn C, Anatomi dan Fisiologi untuk paramedis. Jakarta: PT Gramedia Pustaka Umum; . 2010.


Article Metrics

This article has been read : 59 times
PDF file viewed/downloaded : 30 times

Copyright & License


Copyright (c) 2018 Febry Mutiariami Dahlan, Eryati Darwin, Hirowati Ali

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Published by:
Undergraduate Program of Midwifery
Faculty of Medicine - Universitas Andalas - Indonesia
Faculty of Medicine, Universitas Andalas

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.